The science of
ambient physiology.
How millions of clinically labeled pulse waveforms turn everyday smartphone sensors into continuous windows into human biology.
Blood flow has to continuously adapt to what the body needs.
Blood delivers oxygen, nutrients, hormones, and immune factors throughout the entire human body. As physiological state shifts — whether from autonomic stress, metabolic spikes, fluid volume changes, or inflammatory responses — circulation must adjust instantaneously.
These microvascular adjustments alter peripheral resistance, arterial wall stiffness, stroke volume, dicrotic notch timing, and diastolic decay slopes across the entire pulse contour.
Different physiological systems imprint on the blood-flow wave in distinct ways.
No single scalar metric (like heart rate alone) tells the complete story. The entire high-dimensional wave structure reflects coordinated multi-organ dynamics.
Your neighborhood helps tell us what your representation means.
Where you sit in high-dimensional physiological space provides continuous clinical context without relying on rigid, one-size-fits-all diagnostic cutoffs.
One measurement, one location in latent space.
Your 30-second smartphone scan is translated into a high-dimensional embedding vector. In this space, every coordinate represents a distinct combination of microvascular compliance, autonomic balance, and pulsatile dynamics.
And movement tells us when something changes.
Your neighborhood provides context. Your movement reveals change. By tracking an individual's trajectory over time, Preemptive decodes three fundamental vectors of physiological inflection.
How the model characterizes a baseline departure.
Direction
"Where did it move?"
Determines which underlying physiological systems or latent axes changed — whether vascular resistance, parasympathetic vagal recovery, cardiac output, or metabolic tone.
Distance
"How much did it change?"
Quantifies the statistical magnitude of departure from the user's established rolling personal normal, filtering out random noise.
Persistence
"Is the change sustained?"
Distinguishes between a transient 1-day spike (e.g. poor sleep or heavy meal) and a sustained 4-day trajectory shift that indicates clinical illness or medication response.
One learned representation. Many distinct downstream tasks.
These tasks demonstrate empirical evidence that a single foundation embedding contains rich, separable information across cardiovascular, metabolic, autonomic, and biological age axes.
Four years of continuous physiology paired with verified clinical outcomes.
Raw optical signals without deep clinical ground truth are merely noise. Preemptive couples millions of raw pulse waveforms with comprehensive EHR trajectories, vitals data, and lab outcomes.
Collaborate on clinical trials, validation, and biomedical AI research.
We partner with academic medical centers, clinical research organizations, biopharma trialists, and health AI researchers to pioneer continuous physiological intelligence.